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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733614
Species: Mus musculus
RGD Object: Gene
Symbol: Gsta3
Name: glutathione S-transferase, alpha 3
Acc ID: CHEBI:76359
Term: butylated hydroxyanisole
Definition: A mixture of 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. Is is used as an antioxidant and preservative in food, cosmetics, pharmaceuticals, rubber and petroleum products.
Chemical ID: MESH:D002083
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta3increases expressionEXP 6480464CTDButylated Hydroxyanisole results in increased expression of GSTA1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTA1 protein; Butylated Hydroxyanisole results in increased expression of GSTA3 proteinPMID:11309284 PMID:11991805 PMID:16426233 PMID:1859377 PMID:2049074 PMID:2597111 PMID:29086419
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