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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:76359
Term: butylated hydroxyanisole
Definition: A mixture of 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. Is is used as an antioxidant and preservative in food, cosmetics, pharmaceuticals, rubber and petroleum products.
Chemical ID: MESH:D002083
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3increases expressionISOAbcc3 (Mus musculus)6480464CTDButylated Hydroxyanisole results in increased expression of ABCC3 mRNAPMID:15833929
Abcc3multiple interactionsISOAbcc3 (Mus musculus)6480464CTD[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNAPMID:15833929
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