Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	3087
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Mgmt
Name:	O-6-methylguanine-DNA methyltransferase

Acc ID:	CHEBI:76261
Term:	1-nitropropane
Definition:	A nitroalkane that is propane substituted at C-1 by a nitro group.
Chemical ID:	MESH:C035314

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Mgmt	increases expression	EXP		6480464	CTD	1-nitropropane results in increased expression of MGMT mRNA	PMID:17070881

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.