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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737309
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARA
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:7622
Term: norathyriol
Definition: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C.
Chemical ID: MESH:C069053
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARAmultiple interactionsEXP 6480464CTDnorathyriol inhibits the reaction [GW 7647 results in increased activity of PPARA protein]PMID:18393431
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