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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1h4
Name: nuclear receptor subfamily 1, group H, member 4
Acc ID: CHEBI:76126
Term: (+)-epicatechin-3-O-gallate
Definition: A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3S)-hydroxy group of (+)-epicatechin.
Chemical ID: MESH:C062669
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1h4increases activityISONR1H4 (Homo sapiens)6480464CTDepicatechin gallate results in increased activity of NR1H4 proteinPMID:22178739
Nr1h4multiple interactionsISONR1H4 (Homo sapiens)6480464CTD[epicatechin gallate co-treated with gallocatechol] results in increased activity of NR1H4 proteinPMID:22178739
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