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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312132
Species: Mus musculus
RGD Object: Gene
Symbol: Polrmt
Name: polymerase (RNA) mitochondrial (DNA directed)
Acc ID: CHEBI:76004
Term: dimethyl fumarate
Definition: An enoate ester resulting from the formal condensation of both carboxy groups of fumaric acid with methanol. Used for treatment of adults with relapsing forms of multiple sclerosis.
Chemical ID: MESH:C056020
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Polrmtincreases expressionEXP 6480464CTDDimethyl Fumarate results in increased expression of POLRMT mRNAPMID:27277809
Polrmtmultiple interactionsEXP 6480464CTDNFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of POLRMT mRNA]PMID:27277809
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