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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Thra
Name: thyroid hormone receptor alpha
Acc ID: CHEBI:7590
Term: nitrofen
Definition: An organic molecular entity that has formula C12H7Cl2NO3.
Chemical ID: MESH:C007350
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Thradecreases expressionEXP 6480464CTDnitrofen results in decreased expression of THRA mRNAPMID:11685700
Thramultiple interactionsISOTHRA (Homo sapiens)6480464CTDnitrofen binds to and results in increased activity of THRA proteinPMID:15585367
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