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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735043
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myd88
Name: MYD88, innate immune signal transduction adaptor
Acc ID: CHEBI:75718
Term: genkwanin
Definition: A monomethoxyflavone that is apigenin in which the hydroxy group at position 7 is methylated.
Chemical ID: MESH:C014568
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myd88multiple interactionsISOMYD88 (Homo sapiens)6480464CTDgenkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of MYD88 protein]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of MYD88 protein]]PMID:34481870
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