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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621826
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pfn2
Name: profilin 2
Acc ID: CHEBI:75701
Term: sarin
Definition: A racemate composed of equal amounts of (R)- and (S)-sarin. A potent and irreversible inhibitor of acetylcholinesterase that is toxic to the nervous system and is employed as a chemical warfare agent.
Chemical ID: MESH:D012524
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pfn2decreases expressionEXP 6480464CTDSarin results in decreased expression of PFN2 proteinPMID:28973502
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