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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620942
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnaja1
Name: DnaJ heat shock protein family (Hsp40) member A1
Acc ID: CHEBI:75701
Term: sarin
Definition: A racemate composed of equal amounts of (R)- and (S)-sarin. A potent and irreversible inhibitor of acetylcholinesterase that is toxic to the nervous system and is employed as a chemical warfare agent.
Chemical ID: MESH:D012524
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7344136480464CTDSarin results in decreased expression of DNAJA1 mRNA

PMID:19522546
increases expressionISORGD:7344136480464CTDSarin results in increased expression of DNAJA1 mRNA

PMID:19522546
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.