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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731489
Species: Mus musculus
RGD Object: Gene
Symbol: Map3k8
Name: mitogen-activated protein kinase kinase kinase 8
Acc ID: CHEBI:75630
Term: procyanidin B3
Definition: A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 8' in alpha-configuration. It can be found in red wine, in barley, in beer, in peach or in Jatropha macrantha, the Huanarpo Macho.
Chemical ID: MESH:C479581
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k8multiple interactionsEXP 6480464CTD[Eicosapentaenoic Acid co-treated with procyanidin B3] inhibits the reaction [Lipopolysaccharides results in increased expression of MAP3K8 mRNA]; procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of MAP3K8 mRNA]PMID:22169119
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