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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10370
Species: Mus musculus
RGD Object: Gene
Symbol: Cnr1
Name: cannabinoid receptor 1
Acc ID: CHEBI:75431
Term: ghrelin
Definition: A 28-membered appetite-stimulating polypeptide consisting of Gly, Ser, Ser(octanoyl), Phe, Leu, Ser, Pro, Glu, His, Gln, Arg, Val, Gln, Gln, Arg, Lys, Glu, Ser, Lys, Lys, Pro, Pro, Ala, Lys, Leu, Gln, Pro and Arg residues joined in sequence. The O-n-octanoylation of the side-chain hydroxy group of serine-3 (Ser3) is essential for ghrelin's activity.
Chemical ID: MESH:D054439
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cnr1multiple interactionsISOCnr1 (Rattus norvegicus)6480464CTDGhrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA]PMID:31468622
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