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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735541
Species: Homo sapiens
RGD Object: Gene
Symbol: BAD
Name: BCL2 associated agonist of cell death
Acc ID: CHEBI:75417
Term: dibenzoylmethane
Definition: A beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects.
Chemical ID: MESH:C061481
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BADincreases expressionEXP 6480464CTDdibenzoylmethane results in increased expression of BAD proteinPMID:21523861
BADmultiple interactionsEXP 6480464CTDODC1 protein inhibits the reaction [dibenzoylmethane results in increased expression of BAD protein]PMID:21523861
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