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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308946
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hm13
Name: histocompatibility minor 13
Acc ID: CHEBI:75408
Term: sulindac sulfide
Definition: An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity.
Chemical ID: MESH:C025462
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects bindingISORGD:13190136480464CTDsulindac sulfide binds to HM13 protein

PMID:17932033
multiple interactionsISORGD:13190136480464CTDsulindac sulfide inhibits the reaction [L 685458 binds to HM13 protein]

PMID:17932033
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.