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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10563
Species: Mus musculus
RGD Object: Gene
Symbol: Fabp1
Name: fatty acid binding protein 1, liver
Acc ID: CHEBI:75408
Term: sulindac sulfide
Definition: An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity.
Chemical ID: MESH:C025462
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fabp1increases expressionISOFABP1 (Homo sapiens)6480464CTDsulindac sulfide analog results in increased expression of FABP1 proteinPMID:17602619 PMID:18665581
Fabp1multiple interactionsISOFABP1 (Homo sapiens)6480464CTD2-chloro-5-nitrobenzanilide inhibits the reaction [sulindac sulfide analog results in increased expression of FABP1 protein]; PPARG protein affects the reaction [sulindac sulfide analog results in increased expression of FABP1 protein]PMID:17602619 PMID:18665581
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