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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619569
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCC2
Name: ATP binding cassette subfamily C member 2
Acc ID: CHEBI:75404
Term: tyrphostin AG 1478
Definition: A member of the class of quinazolines that is quinazoline substituted by methoxy groups at positions 6 and 7 and a (3-chlorophenyl)nitrilo group at position 4. It acts as an epidermal growth factor receptor antagonist.
Chemical ID: MESH:C101044
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCC2multiple interactionsISOAbcc2 (Rattus norvegicus)6480464CTDRTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]PMID:25813982
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