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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10430
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp11b2
Name: cytochrome P450, family 11, subfamily b, polypeptide 2
Acc ID: CHEBI:75400
Term: calmidazolium
Definition: An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein.
Chemical ID: MESH:C031938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11b2multiple interactionsISOCYP11B2 (Homo sapiens)6480464CTDcalmidazolium inhibits the reaction [Potassium results in increased expression of CYP11B2 mRNA]PMID:12193581
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