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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732547
Species: Homo sapiens
RGD Object: Gene
Symbol: MSN
Name: moesin
Acc ID: CHEBI:75393
Term: Y-27632
Definition: A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme.
Chemical ID: MESH:C108830
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MSNincreases phosphorylationISOMsn (Rattus norvegicus)6480464CTDY 27632 deficiency results in increased phosphorylation of MSN proteinPMID:14732730
MSNmultiple interactionsISOMsn (Rattus norvegicus)6480464CTDY 27632 inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MSN protein]PMID:30783172
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