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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620890
Species: Mus musculus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP-binding cassette, sub-family B member 1A
Acc ID: CHEBI:75283
Term: miltefosine
Definition: A phospholipid that is the hexadecyl monoester of phosphocholine.
Chemical ID: MESH:C039128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1adecreases response to substanceISOABCB1 (Homo sapiens)6480464CTDABCB1 protein results in decreased susceptibility to miltefosinePMID:11355955
Abcb1amultiple interactionsISOABCB1 (Homo sapiens)6480464CTDmiltefosine binds to and results in decreased activity of ABCB1 proteinPMID:11355955
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