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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732474
Species: Mus musculus
RGD Object: Gene
Symbol: Grb2
Name: growth factor receptor bound protein 2
Acc ID: CHEBI:75253
Term: phenylarsine oxide
Definition: An arsine oxide derived from phenylarsine.
Chemical ID: MESH:C029341
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:6197586480464CTD[oxophenylarsine results in decreased phosphorylation of PLCG1 protein] inhibits the reaction [PLCG1 protein binds to GRB2 protein]

PMID:9281317
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.