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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621480
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srd5a2
Name: steroid 5 alpha-reductase 2
Acc ID: CHEBI:75170
Term: zaragozic acid A
Definition: A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase.
Chemical ID: MESH:C075117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srd5a2increases expressionEXP 6480464CTDsqualestatin 1 results in increased expression of SRD5A2 mRNAPMID:27225895
Srd5a2decreases expressionISOSrd5a2 (Mus musculus)6480464CTDsqualestatin 1 results in decreased expression of SRD5A2 mRNAPMID:27225895
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