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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2326
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Acc ID: CHEBI:75142
Term: N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal
Definition: A tripeptide that is L-leucyl-L-leucyl-L-leucine in which the C-terminal carboxy group has been reduced to the corresponding aldehyde and the N-terminal amino group is protected as its benzyloxycarbonyl derivative.
Chemical ID: MESH:C072553
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases ubiquitinationISORGD:691216480464CTDbenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of CEBPA protein

PMID:19662097
multiple interactionsISORGD:691216480464CTDbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NSC606985 results in decreased expression of CEBPA protein]

PMID:19662097
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.