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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308131
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arih1
Name: ariadne RBR E3 ubiquitin protein ligase 1
Acc ID: CHEBI:75142
Term: N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal
Definition: A tripeptide that is L-leucyl-L-leucyl-L-leucine in which the C-terminal carboxy group has been reduced to the corresponding aldehyde and the N-terminal amino group is protected as its benzyloxycarbonyl derivative.
Chemical ID: MESH:C072553
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13177266480464CTDbenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein

PMID:25624349
multiple interactionsISORGD:13177266480464CTD2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein]

PMID:25624349
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.