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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735591
Species: Homo sapiens
RGD Object: Gene
Symbol: IL10
Name: interleukin 10
Acc ID: CHEBI:75095
Term: chrysin
Definition: A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.
Chemical ID: MESH:C043561
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL10multiple interactionsEXP 6480464CTDchrysin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]PMID:30016632
IL10multiple interactionsISOIl10 (Mus musculus)6480464CTDchrysin inhibits the reaction [Diazinon results in increased expression of IL10 mRNA]; chrysin inhibits the reaction [Oxidopamine results in decreased expression of IL10 protein]PMID:29054324 PMID:36114367
IL10multiple interactionsISOIl10 (Rattus norvegicus)6480464CTDchrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL10 protein]; chrysin inhibits the reaction [Freund's Adjuvant results in decreased expression of IL10 protein]PMID:24932515 PMID:37263553
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