GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcg2 | decreases activity | EXP | | 6480464 | CTD | chrysin results in decreased activity of ABCG2 protein | PMID:17093006 | Abcg2 | multiple interactions | EXP | | 6480464 | CTD | chrysin inhibits the reaction [ABCG2 protein affects the transport of Nitrofurantoin] | PMID:19732493 | Abcg2 | decreases activity | ISO | ABCG2 (Homo sapiens) | 6480464 | CTD | chrysin results in decreased activity of ABCG2 protein | PMID:20457140 | Abcg2 | decreases expression | ISO | ABCG2 (Homo sapiens) | 6480464 | CTD | chrysin results in decreased expression of ABCG2 mRNA | PMID:20816778 | Abcg2 | increases expression | ISO | ABCG2 (Homo sapiens) | 6480464 | CTD | chrysin results in increased expression of ABCG2 mRNA; chrysin results in increased expression of ABCG2 protein | PMID:17077187 PMID:20457140 | Abcg2 | multiple interactions | ISO | ABCG2 (Homo sapiens) | 6480464 | CTD | [chrysin results in decreased activity of ABCG2 protein] which results in decreased export of Topotecan; chrysin inhibits the reaction [ABCG2 protein results in increased secretion of Mitoxantrone]; chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin] | PMID:17093006 PMID:20457140 | Abcg2 | multiple interactions | ISO | Abcg2 (Mus musculus) | 6480464 | CTD | chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin] | PMID:17093006 | |
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