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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731381
Species: Mus musculus
RGD Object: Gene
Symbol: Aifm1
Name: apoptosis-inducing factor, mitochondrion-associated 1
Acc ID: CHEBI:7496
Term: nelfinavir
Definition: An aryl sulfide that is used (as its mesylate salt) for treatment of HIV and also exhibits some anticancer properties.
Chemical ID: MESH:D019888
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aifm1affects localizationEXP 6480464CTDNelfinavir affects the localization of AIFM1 proteinPMID:18497877
Aifm1decreases secretionEXP 6480464CTDNelfinavir results in decreased secretion of AIFM1 proteinPMID:18497877
Aifm1decreases transportEXP 6480464CTDNelfinavir results in decreased transport of AIFM1 proteinPMID:18497877
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