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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3070
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnajb9
Name: DnaJ heat shock protein family (Hsp40) member B9
Acc ID: CHEBI:7494
Term: nefazodone
Definition: A N-alkylpiperazine that has formula C25H32ClN5O2.
Chemical ID: MESH:C051752
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnajb9increases expressionEXP 6480464CTDnefazodone results in increased expression of DNAJB9 mRNAPMID:24136188
Dnajb9increases expressionISODNAJB9 (Homo sapiens)6480464CTDnefazodone results in increased expression of DNAJB9 mRNAPMID:32152650
Dnajb9multiple interactionsISODNAJB9 (Homo sapiens)6480464CTD[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of DNAJB9 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB9 mRNAPMID:32152650 PMID:33819548
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