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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737208
Species: Mus musculus
RGD Object: Gene
Symbol: Chrm3
Name: cholinergic receptor, muscarinic 3, cardiac
Acc ID: CHEBI:7449
Term: nafenopin
Definition: A racemate comprising equimolar amounts of (R)- and (S)-nafenopin. It is a peroxisome proliferator that is used experimentally to promote liver tumors. It has been used as an hypolipidemic agent.
Chemical ID: MESH:D009255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrm3increases expressionISOChrm3 (Rattus norvegicus)6480464CTDNafenopin results in increased expression of CHRM3 proteinPMID:10903494
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