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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737288
Species: Homo sapiens
RGD Object: Gene
Symbol: TNFRSF1A
Name: TNF receptor superfamily member 1A
Acc ID: CHEBI:74023
Term: dioscin
Definition: A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage.
Chemical ID: MESH:C019357
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFRSF1Aincreases expressionEXP 6480464CTDdioscin results in increased expression of TNFRSF1A mRNA; dioscin results in increased expression of TNFRSF1A proteinPMID:22334414 PMID:29990575 PMID:33359023
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