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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619570
Species: Homo sapiens
RGD Object: Gene
Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:74023
Term: dioscin
Definition: A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage.
Chemical ID: MESH:C019357
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK3multiple interactionsEXP 6480464CTDdioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK3 protein]

PMID:25111127
MAPK3multiple interactionsISORGD:30466480464CTDdioscin inhibits the reaction [Ethanol results in increased phosphorylation of MAPK3 protein]

PMID:24146112
MAPK3multiple interactionsISORGD:6195716480464CTDdioscin inhibits the reaction [Ethanol results in increased phosphorylation of MAPK3 protein]

PMID:24146112
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