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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:73295
Term: WIN 55212-2
Definition: A organic heterotricyclic compound that is 5-methyl-3-(morpholin-4-ylmethyl)-2,3-dihydro[1,4]oxazino[2,3,4-hi]indole substituted at position 6 by a 1-naphthylcarbonyl group.
Chemical ID: MESH:C070417
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:691656480464CTDWin 55212-2 results in increased expression of DDIT3 mRNA

PMID:30502353
multiple interactionsISORGD:691656480464CTDAcetylcysteine inhibits the reaction [Win 55212-2 results in increased expression of DDIT3 mRNA], methyl-beta-cyclodextrin inhibits the reaction [Win 55212-2 results in increased expression of DDIT3 mRNA]

PMID:30502353
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.