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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621282
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Birc3
Name: baculoviral IAP repeat-containing 3
Acc ID: CHEBI:73286
Term: 3-iodobenzyl-5'-N-methylcarboxamidoadenosine
Definition: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group.
Chemical ID: MESH:C084956
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc3decreases expressionISOBIRC3 (Homo sapiens)6480464CTDN(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of BIRC3 mRNAPMID:16088125
Birc3decreases response to substanceISOBIRC3 (Homo sapiens)6480464CTDBIRC3 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosinePMID:16088125
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