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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351047
Species: Homo sapiens
RGD Object: Gene
Symbol: IL12A
Name: interleukin 12A
Acc ID: CHEBI:73286
Term: 3-iodobenzyl-5'-N-methylcarboxamidoadenosine
Definition: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group.
Chemical ID: MESH:C084956
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL12Amultiple interactionsEXP 6480464CTDN(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]; Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]PMID:16116186
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