GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adora1 | multiple interactions | EXP | | 6480464 | CTD | 1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein; 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 mRNA]]; 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 protein]]; [1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to 2-chloro-N(6)cyclopentyladenosine | PMID:10642308 PMID:10677590 PMID:11311893 PMID:15641640 PMID:18313046 PMID:18608257 PMID:19749167 PMID:19966059 | Adora1 | affects binding | ISO | ADORA1 (Homo sapiens) | 6480464 | CTD | 1,3-dipropyl-8-cyclopentylxanthine binds to ADORA1 protein | PMID:21186795 PMID:21675777 | Adora1 | multiple interactions | ISO | Adora1 (Mus musculus) | 6480464 | CTD | 1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein; [1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to Oxygen deficiency; [1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein] which results in increased susceptibility to cobaltous chloride | PMID:18727925 PMID:22164264 PMID:23437309 | | ||||||||||||||||||||||
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