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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3952
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:73224
Term: allyl isothiocyanate
Definition: An isothiocyanate with the formula CH2=CHCH2N=C=S. A colorless oil with boiling point 152degreeC, it is responsible for the pungent taste of mustard, horseradish, and wasabi.
Chemical ID: MESH:C004471
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1multiple interactionsISOVcam1 (Mus musculus)6480464CTDallyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; allyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]PMID:28483571
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