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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2466
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2b1
Name: cytochrome P450, family 2, subfamily b, polypeptide 1
Acc ID: CHEBI:73172
Term: acifluorfen
Definition: A member of the class of benzoic acids that is 2-nitrobenzoic acid in which the hydrogen at position 5 is replaced by a 2-chloro-4-(trifluoromethyl)phenoxy group. It is a herbicide used for the post-emergence control of a variety of annual broadleaf weeds.
Chemical ID: MESH:C018425
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b1increases expressionISORGD:15583116480464CTDacifluorfen results in increased expression of CYP2B10 mRNA

PMID:26928356
Cyp2b1multiple interactionsISORGD:15583116480464CTDNR1I3 gene mutant form inhibits the reaction [acifluorfen results in increased expression of CYP2B10 mRNA]

PMID:26928356
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