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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:73167
Term: concanamycin A
Definition: A concanamycin in which the lactone ring contains 4 double bonds and is substituted by 4 methyl groups, 2 hydroxy groups, 2 methoxy groups and an ethyl group.
Chemical ID: MESH:C036978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISORGD:102896480464CTDconcanamycin A inhibits the reaction [enterotoxin C, staphylococcal analog results in increased activity of CASP3 protein], concanamycin A inhibits the reaction [enterotoxin C, staphylococcal results in increased activity of CASP3 protein]

PMID:27742270
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.