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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:72959
Term: N-hexadecanoylsphingosine
Definition: A N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl).
Chemical ID: MESH:C097760
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDN-palmitoylsphingosine results in increased expression of DDIT3 mRNA

PMID:28223344
multiple interactionsEXP 6480464CTD[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA, tauroursodeoxycholic acid inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA], tauroursodeoxycholic acid inhibits the reaction [N-palmitoylsphingosine results in increased expression of DDIT3 mRNA]

PMID:28223344
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.