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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620330
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cs
Name: citrate synthase
Acc ID: CHEBI:72959
Term: N-hexadecanoylsphingosine
Definition: A N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl).
Chemical ID: MESH:C097760
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csdecreases expressionISOCs (Mus musculus)6480464CTDN-palmitoylsphingosine results in decreased expression of CS mRNAPMID:28223344
Csmultiple interactionsISOCs (Mus musculus)6480464CTD[N-palmitoylsphingosine co-treated with Dietary Fats] results in decreased activity of CS protein; ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in decreased activity of CS protein]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in decreased expression of CS mRNA]PMID:28223344
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