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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730847
Species: Mus musculus
RGD Object: Gene
Symbol: Casp8
Name: caspase 8
Acc ID: CHEBI:72767
Term: demethoxyfumitremorgin C
Definition: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid, consisting of fumitremorgin C lacking the 9-methoxy substituent.
Chemical ID: MESH:C100698
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp8increases activityISOCASP8 (Homo sapiens)6480464CTDdemethoxyfumitremorgin C results in increased activity of CASP8 proteinPMID:28359723
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