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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69410
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Asah2
Name: N-acylsphingosine amidohydrolase 2
Acc ID: CHEBI:72544
Term: flavonoids
Definition: Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them.
Chemical ID: MESH:D005419
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Asah2multiple interactionsEXP 6480464CTDFlavonoids inhibits the reaction [Carbon Tetrachloride results in decreased activity of ASAH2 protein]PMID:18226198
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