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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553810
Species: Mus musculus
RGD Object: Gene
Symbol: Bmp7
Name: bone morphogenetic protein 7
Acc ID: CHEBI:72312
Term: pasireotide
Definition: A six-membered homodetic cyclic peptide composed from L-phenylglycyl, D-tryptophyl, L-lysyl, O-benzyl-L-tyrosyl, L-phenylalanyl and modified L-hydroxyproline residues joined in sequence. A somatostatin analogue with pharmacologic properties mimicking those of the natural hormone somatostatin; used (as its diaspartate salt) for treatment of Cushing's disease.
Chemical ID: MESH:C517782
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13442346480464CTDpasireotide promotes the reaction [BMP7 protein results in increased expression of ID1 mRNA]

PMID:23137853
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.