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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3469
Species: Rattus norvegicus
RGD Object: Gene
Symbol: RT1-Bb
Name: RT1 class II, locus Bb
Acc ID: CHEBI:71941
Term: tolmetin
Definition: A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Chemical ID: MESH:D014046
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RT1-Bbaffects expressionISOHLA-DQB1 (Homo sapiens)6480464CTDTolmetin affects the expression of HLA-DQB1 mRNAPMID:25811541
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