Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67390
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Orm1
Name: orosomucoid 1
Acc ID: CHEBI:71415
Term: nitrofurantoin
Definition: An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA.
Chemical ID: MESH:D009582
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Orm1increases expressionEXP 6480464CTDNitrofurantoin results in increased expression of ORM1 mRNA Nitrofurantoin results in increased expression of ORM1 protein

PMID:11841787
Go Back to source page   Continue to Ontology report