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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348437
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:71045
Term: bisdemethoxycurcumin
Definition: A beta-diketone that is methane in which two of the hydrogens are substituted by 4-hydroxycinnamoyl groups.
Chemical ID: MESH:C034786
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP9decreases expressionEXP 6480464CTDbisdemethoxycurcumin results in decreased expression of MMP9 proteinPMID:35735092
MMP9multiple interactionsEXP 6480464CTDbisdemethoxycurcumin results in decreased secretion of and results in decreased activity of MMP9 proteinPMID:18495463
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