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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731889
Species: Homo sapiens
RGD Object: Gene
Symbol: CDK1
Name: cyclin dependent kinase 1
Acc ID: CHEBI:71019
Term: omacetaxine mepesuccinate
Definition: A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.
Chemical ID: MESH:C001652
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDK1increases expressionEXP 6480464CTDHomoharringtonine results in increased expression of CDK1 proteinPMID:31726078
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