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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737520
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Acc ID: CHEBI:70973
Term: monoethyl phthalate
Definition: A phthalic acid monoester resulting from the condensation of one of the carboxy groups of phthalic acid with ethanol.
Chemical ID: MESH:C581825
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp19a1multiple interactionsEXP 6480464CTD[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP19A1 mRNAPMID:31884101
Cyp19a1increases expressionISOCYP19A1 (Homo sapiens)6480464CTDmonoethyl phthalate results in increased expression of CYP19A1 mRNAPMID:29089286
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