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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69401
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acsl4
Name: acyl-CoA synthetase long-chain family member 4
Acc ID: CHEBI:70778
Term: GW 7647
Definition: A monocarboxylic acid that is 2-(phenylsulfanyl)isobutyric acid in which the phenyl group is substituted at the para- position by a 3-aza-7-cyclohexylhept-1-yl group in which the nitrogen is acylated by a (cyclohexylamino)carbonyl group.
Chemical ID: MESH:C453899
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13446936480464CTDGW 7647 results in increased expression of ACSL4 mRNA

PMID:30611723
multiple interactionsISORGD:13446936480464CTD[GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA

PMID:30611723
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.