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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3411
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Proc
Name: protein C, inactivator of coagulation factors Va and VIIIa
Acc ID: CHEBI:70708
Term: dienogest
Definition: A steroid hormone that is 17beta-hydroxy-3-oxoestra-4,9-diene substituted at position 17 by a cyanomethyl group. Used as an oral contraceptive.
Chemical ID: MESH:C023635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7373216480464CTD[Ethinyl Estradiol co-treated with dienogest] results in increased activity of PROC protein

PMID:15288212
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.