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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68534
Species: Mus musculus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:70436
Term: platycodin D
Definition: A triterpenoid saponin that has formula C57H92O28.
Chemical ID: MESH:C108953
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtordecreases phosphorylationISOMTOR (Homo sapiens)6480464CTDplatycodin D results in decreased phosphorylation of MTOR proteinPMID:23867902
Mtormultiple interactionsISOMTOR (Homo sapiens)6480464CTD[platycodin D co-treated with Imatinib Mesylate] results in decreased phosphorylation of and results in decreased expression of MTOR proteinPMID:29552859
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